Enter your keywords
HOME
About Us
NEWSLETTER
To search AlzRisk, use the "Keyword" search on the
AlzRisk search page
.
NEWS
All News
Conference Coverage
Series
WEBINARS
All Webinars
Databases
AlzBiomarker
AlzPedia
AlzRisk
Antibodies
Genetics
AlzGene
HEX
Mutations
Protocols
Research Models
Therapeutics
PAPERS
All Papers
Papers of the Week
Milestone
Alzforum Recommends
PROFESSIONAL RESOURCES
Conference Calendar
Grants
Jobs
Member Directory
ABOUT AD
AD Overview
Early-Onset Familial
The HBO Alzheimer's Project
Supported Browsers
MY ALZFORUM
My AlzForum Home
View Library
View Notifications
Set Notifications
Edit Profile
AlzRisk Paper Detail
Risk Factors
Alcohol
B Vitamins
Blood Pressure
Cognitive Activity
Diabetes Mellitus
Dietary Pattern
Head injury
Homocysteine
Hormone Therapy
Inflammatory Biomarkers
Non-Steroidal Anti-Inflammatory Drugs
Nutritional Antioxidants
Obesity
Physical Activity
Statin use
Reference:
Blasko, 2008
Cohort:
Vienna Trans-danube Aging Cohort
Risk Factor:
Homocysteine
Exposure Detail
"Blood samples were collected into polypropylene tubes containing potassium EDTA. The samples were immediately stored on ice and centrifuged within 60 min, and aliquots of plasma were stored at −80 ◦C."
"Homocysteine levels were determined with microparticle enzyme-immunoassay at IMX detection system (Abbott, Wiesbaden, Germany)."
Log-transformed change in homocysteine levels over 2.5 years of follow-up was computed.
Ethnicity Detail
No information on ethnicity was given. However, as the participants were residents of Vienna, they were presumably mostly Caucasian.
Screening and Diagnosis Detail
Screening Method:
CERAD
Consortium to Establish a Registry for Alzheimer's Disease (Morris 1989)
Neuropsych Testing
TMT
Trail Making Test (Reitan 1958)
AD Diagnosis:
NINCDS ADRDA
National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer's Disease and Related Disorders Association Criteria (McKhann 1984)
Covariates & Analysis Detail
Analysis Type:
Logistic regression
AD Covariates:
A
age
E
education
G
gender
APOE4
APOE e4 genotype
CHMTA
change in medial temporal lobe atrophy
CHAB42
change in plasma amyloid-beta 42