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AlzRisk Paper Detail
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Reference: Wang, 2001
Cohort: Kungsholmen Project
Risk Factor: B Vitamins


Exposure Detail
"Baseline serum vitamin B12 and folate levels were assessed according to the recommended procedure for a commercial radioligand kit."

The cut-off point of ≤250 pmol/L was chosen based on prior studies that suggested this threshold to define B12 deficiency in the elderly.

Ethnicity Detail
Participants were sampled from the population of the Kungsholmen district of Stockholm, Sweden. No information on the ethnic background of participants has been provided.

Screening and Diagnosis Detail
AD Diagnosis:
DSM IIIR Diagnostic and Statistical Manual III-Revised

Dementia and type of dementia were diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders,third edition, revised[22]. More specifically, for an AD diagnosis gradual onset and progressive deterioration of dementia were required and all other specific causes of dementia had to be excluded.

Covariates & Analysis Detail
Analysis Type:
Cox proportional hazards regression

AD Covariates:
Aage
Eeducation
Ggender

TD Covariates:
Aage
Eeducation
Ggender