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Non-Steroidal Anti-Inflammatory Drugs
Cardiovascular Health Cognition Study/Cardiovascular Health Study Cognition Study
The interviewers ascertained exposure information via an annual medication inventory. The investigators reported results separately for ever/never statin use, lipophilic statin use, less lipohilic statin use, current/past/never use, and duration of use. This entry pertains to results on less lipophilic statin use with a 1 year time lag.
The investigators compared incident AD risk in two groups: the group of participants who used less lipophilic statins (atorvastatin calcium, pravastatin sodium, and fluvastatin sodium) at baseline or during follow-up up to a year prior to AD assessment ("Ever used") and the reference group of participants who did not use statins or non-statin LLAs ("Never used"). The article does not provide the proportion of participants that used less lipophilic statins.
Caucasian participants contributed 91% of person-time.
Cohort members older than eighty years of age contributed fifty-four percent of person-time. The article does not provide the average age for members of this cohort.
Screening and Diagnosis Detail
Mini-Mental State Examination (Folstein 1975)
Covariates & Analysis Detail
Cox proportional hazards regression