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AlzRisk Cohort Detail

Cohort: Kaiser Permanente Medical Care Program of Southern California
Risk Factors:

Introduction to the Cohort
Kaiser Permanente of Southern California is a non-profit, group-practice health insurance program. Kaiser Permanente members are representative of the socio-demographic profile of the local population. Computer-stored prescription data from the KPSC Pharmacy Information Management System is available beginning in 1992. A sub-cohort was defined among member of this healthcare plan, based on hormone therapy usage, for a study of hormone therapy and AD risk.

Ethnicity Breakdown
In the sub-cohort described in Petitti 2008, 89% of participants were white, 4% were black, 3% were Hispanic and 4% were of other or unknown ethnicity. These percentages are not representative of the health plan members as a whole.

Diagnosis & Evaluation Methods
See Petitti et al. 2008 for a detailed description.

Petitti DB, Buckwalter G, Crooks VC, Chiu V. Prevalence of dementia in users of hormone replacement therapy as defined by prescription data. Journal of Gerontology 2002;57A:M532-M538.

Petitti DB, Crooks VC, Chiu V, Buckwalter JG, Chui HC. Incidence of dementia in long-term hormone users. American Journal of Epidemiology 2008;167:692-700.